靶标 NEDD9 别名 Cas like docking;Cas scaffolding protein family member 2;CAS-L;CAS2;CasL;CASL_HUMAN;CASS2;Crk associated substrate related;Crk associated substrate related protein;CRK-associated substrate-related protein;dJ49G10.2 (Enhancer of Filamentation 1 (HEF1));dJ49G10.2;dJ761I2.1 (enhancer of filamentation (HEF1));dJ761I2.1;Enhancer of filamentation 1;Enhancer of filamentation 1 p55;HEF 1;HEF1;NEDD-9;Nedd9;Neural precursor cell expressed developmentally down-regulated protein 9;P105;Renal carcinoma antigen NY-REN-12 宿主 Rabbit 稀释比例 IHC 1:100-300. Gene ID 4739 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q14511 蛋白分子量 19/93kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. 亚细胞定位 Cytoplasm Nucleus Cell membrane 免疫原 Recombinant protein of human NEDD9 亚型 IgG 纯化方法 Affinity purification 背景资料 Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May function in transmitting growth control signals between focal adhesions at the cell periphery and the mitotic spindle in response to adhesion or growth factor signals initiating cell proliferation. May play an important role in integrin beta-1 or B cell antigen receptor (BCR) mediated signaling in B- and T-cells. Integrin beta-1 stimulation leads to recruitment of various proteins including CRK, NCK and SHPTP2 to the tyrosine phosphorylated form. Required for correct adhesion and migration of T-cells (PubMed:17174122). Public Immunogen Range 1-175aa 克隆类型 Polyclonal Antibody 交叉反应 Human;Mouse 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。