英文名称 Anti-TRADD Polyclonal Antibody 靶标 TRADD 别名 Hs.89862; TNFRSF1A associated via death domain; 宿主 Rabbit 预测交叉反应 Cow 稀释比例 WB 1:1000-3000. Gene ID 8717 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q15628 蛋白分子量 28/34kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm Nucleus 免疫原 A synthetic peptide of human TRADD 亚型 IgG 纯化方法 Affinity purification 背景资料 The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B. Public Immunogen Range 30-80/312aa 克隆类型 Polyclonal Antibody 交叉反应 Human;Mouse 应用 WB 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。