靶标 NCK1 别名 Cytoplasmic protein NCK1;Melanoma Nck protein;MGC12668;NCK 1;NCK adaptor protein 1;NCK alpha;NCK;NCK tyrosine kinase;Nck-1;NCK1;NCK1_HUMAN;NCKalpha;Non catalytic region of tyrosine kinase;SH2/SH3 adaptor protein NCK alpha;SH2/SH3 adaptor protein NCK-alpha 宿主 Rabbit 稀释比例 IHC 1:100-300. Gene ID 4690 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot P16333 蛋白分子量 36/43kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. 亚细胞定位 Nucleus Cytoplasm Cell membrane 免疫原 Recombinant protein of human NCK1 亚型 IgG 纯化方法 Affinity purification 背景资料 Adapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. Modulates the activation of EIF2AK2/PKR by dsRNA. May play a role in cell adhesion and migration through interaction with ephrin receptors. Public Immunogen Range 1-349aa 克隆类型 Polyclonal Antibody 交叉反应 Human;Mouse 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。