靶标 TP63 别名 AIS;B(p51A);B(p51B);EEC3;KET;LMS;NBP;OFC8;RHS;SHFM4;TP53CP;TP53L;TP73L;p40;p51;p53CP;p63;p73H;p73L;TP63 宿主 Rabbit 稀释比例 WB 1:1000-3000. Gene ID 8626 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q9H3D4 蛋白分子量 45/47/51/56/57/58/62/63/65/66/68/76/77kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. 亚细胞定位 Nucleus 免疫原 A synthetic peptide of human TP63 亚型 IgG 纯化方法 Affinity purification 背景资料 This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. [provided by RefSeq, Aug 2016] Public Immunogen Range 245-295/680aa 克隆类型 Polyclonal Antibody 交叉反应 Human;Mouse;Rat 应用 WB 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。