靶标 BACE1 别名 APP beta secretase;Asp 2;ASP2;Aspartyl protease 2;BACE 1;BACE;BACE1;BACE1_HUMAN;Beta secretase 1;Beta secretase;Beta site amyloid beta A4 precursor protein cleaving enzyme;Beta site amyloid precursor protein cleaving enzyme 1;Beta site amyloid precursor protein cleaving enzyme;Beta site APP cleaving enzyme 1;Beta site APP cleaving enzyme;Beta-secretase 1;Beta-site amyloid precursor protein cleaving enzyme 1;Beta-site APP cleaving enzyme 1;FLJ90568;HSPC104;Memapsin 2;Memapsin-2;Memapsin2;Membrane associated aspartic protease 2;Membrane-associated aspartic protease 2;Transmembrane aspartic proteinase Asp2 宿主 Rabbit 预测交叉反应 Bovine 稀释比例 WB 1:1000-3000.;IHC 1:50-200. Gene ID 23621 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot P56817 蛋白分子量 42/45/48/51/53/56kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. 亚细胞定位 Cytoplasm Cell membrane 免疫原 Recombinant protein of human BACE1 亚型 IgG 纯化方法 Affinity purification 背景资料 Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase (PubMed:10656250, PubMed:10677483, PubMed:20354142). Public Immunogen Range 6-347aa 克隆类型 Polyclonal Antibody 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。