靶标 MRAP2 别名 C6orf117 宿主 Rabbit 预测交叉反应 ZebraFish 稀释比例 WB 1:1000-3000. Gene ID 112609 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q96G30 蛋白分子量 24kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. 亚细胞定位 Cell membrane Cytoplasm 免疫原 Recombinant protein of human MRAP2 亚型 IgG 纯化方法 Affinity purification 背景资料 Modulator of melanocortin receptor 4 (MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP (By similarity). May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin (ACTH) to MC2R. May also regulate activity of other melanocortin receptors (MC1R, MC3R and MC5R); however, additional evidence is required in vivo. Public Immunogen Range 68-205aa 克隆类型 Polyclonal Antibody 交叉反应 Human Mouse Predicted:ZebraFish 应用 WB 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。