靶标 IPO5 别名 IPO 5 ; IPO5 ; IPO5_HUMAN ; Karyopherin beta 3 ; Karyopherin beta-3 ; KPNB3 ; MGC2068 ; Pse1 ; Ran binding protein 5 ; Ran GTP binding protein 5 ; Ran-binding protein 5 ; RanBP 5 ; RanBP5 ; IMB3 ;KPNB3 ;Pse1 ;RANBP5 ;imp5 宿主 Rabbit 稀释比例 WB 1:1000-3000. ;IHC 1:50-200. Gene ID 3843 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot O00410 蛋白分子量 117/124/126kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. 亚细胞定位 Cytoplasm Nucleus 免疫原 Recombinant protein of human IPO5 亚型 IgG 纯化方法 Affinity purification 背景资料 Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. Public Immunogen Range 1-350aa 克隆类型 Polyclonal Antibody 交叉反应 Human ;Mouse 应用 WB IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。