靶标 TNK2 别名 TNK2;ACK;ACK-1;ACK1;p21cdc42Hs 宿主 Rabbit 稀释比例 WB 1:1000-3000. Gene ID 10188 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q07912 蛋白分子量 60/115/116kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. 亚细胞定位 Cytoplasm 免疫原 A synthetic peptide of human TNK2 亚型 IgG 纯化方法 Affinity purification 背景资料 This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. Public Immunogen Range 350-400/1038aa 克隆类型 Polyclonal Antibody 交叉反应 Human;Mouse;Rat 应用 WB 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。