英文名称 Anti-IGSF3 Polyclonal Antibody 靶标 IGSF3 别名 EWI 3; EWI3; Glu Trp Ile EWI motif containing protein 3; Immunoglobin superfamily member 3; Immunoglobulin superfamily member 3; KIAA0466; MGC117164; V8 antibody; IGSF3_HUMAN. 宿主 Rabbit 稀释比例 WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. ICC 1:100-500. IF 1:50-200. Gene ID 3321 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot O75054 蛋白分子量 133kDa 储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 亚细胞定位 Cell membrane 免疫原 A synthetic peptide of human IGSF3 亚型 IgG 纯化方法 Affinity purification 背景资料 IGSF3, also known as V8 or EWI-3, is a 1,214 amino acid protein. Widely expressed with predominant expression in kidney, placenta and lung, IGSF3 localizes to the membrane and contains an N-terminal signal peptide, eight immunoglobulin (Ig) domains and a transmembrane segment. IGSF3 exhibits strong sequence and structural similarity to CD101 (32% identity), a leukocyte surface protein with seven Ig domains that is believed to play a role in T-cell activation. Despite the structural similarities between IGSF3 and CD101, IGSF3 is not expressed in peripheral blood lymphocytes and does not appear to participate in an immune function. Based on its subcellular localization and the presence of the eight Ig domains, IGSF3 is hypothesized to function as a surface receptor or as a cell adhesion molecule. 克隆类型 Polyclonal Antibody 交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit 应用 WB IHC ICC IF ELISA 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。