靶标 GPR37L1 别名 Endothelin B Receptor Like Protein 2;Endothelin B receptor-like protein 2;ETBR LP 2;ETBR-LP-2;ETBR2_HUMAN;ETBRLP2;G protein coupled receptor 37 like 1;G-protein coupled receptor 37-like 1;Gpr37l1 宿主 Rabbit 稀释比例 WB 1:1000-3000. Gene ID 9283 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot O60883 蛋白分子量 53kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. 亚细胞定位 Cell membrane 免疫原 A synthetic peptide of human GPR37L1 亚型 IgG 纯化方法 Octanoic acid-ammonium sulfate precipitation 背景资料 G-protein coupled receptor. Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade. However, other studies have shown that prosaposin does not increase activit. It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha. Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway. Regulates baseline blood pressure in females and protects against cardiovascular stress in males. Mediates inhibition of astrocyte glutamate transporters and reduction in neuronal N-methyl-D-aspartate receptor activity. Public Immunogen Range 5-55/481aa 克隆类型 Polyclonal Antibody 交叉反应 Human 应用 WB 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。