靶标 ATP6V0A2 别名 a2;A2V ATPase;ARCL;ATP6a2;ATP6N1D;ATP6V0A2;ATPase, H+ transporting, lysosomal V0 subunit a isoform 2;ATPase, H+ transporting, lysosomal V0 subunit a2;Infantile malignant osteopetrosis;J6B7;Lysosomal H(+) transporting ATPase V0 subunit a2;Lysosomal H(+)-transporting ATPase V0 subunit a2;regeneration and tolerance factor;Stv1;TJ6;TJ6M;TJ6s;V ATPase 116 kDa isoform a2;V type proton ATPase 116 kDa subunit a;V type proton ATPase 116 kDa subunit a isoform 2;V-ATPase 116 kDa isoform a2;V-type proton ATPase 116 kDa subunit a isoform 2;Vacuolar proton translocating ATPase 116 kDa subunit a;Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2;Vph1;VPP2_HUMAN;WSS 宿主 Rabbit 预测交叉反应 Bovine 稀释比例 IHC 1:100-300. Gene ID 23545 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q9Y487 蛋白分子量 98kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. 亚细胞定位 Cytoplasm Cell membrane 免疫原 Recombinant protein of human ATP6V0A2 亚型 IgG 纯化方法 Affinity purification 背景资料 Part of the proton channel of V-ATPases. Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633). Public Immunogen Range 50-400aa 克隆类型 Polyclonal Antibody 交叉反应 Human;Mouse 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。