英文名称 Anti-AKAP10 Polyclonal Antibody 靶标 AKAP10 别名 AKAP-10;D-AKAP-2;PRKA10; 宿主 Rabbit 稀释比例 IHC 1:50-200. Gene ID 11216 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot O43572 蛋白分子量 74kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm 免疫原 A synthetic peptide of human AKAP10 亚型 IgG 纯化方法 Affinity purification 背景资料 Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase (By similarity). Public Immunogen Range 25-75/662aa 克隆类型 Polyclonal Antibody 交叉反应 Human 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。