英文名称 Anti-RNF166 Polyclonal Antibody 靶标 RNF166 别名 RING finger protein 166; RN166_HUMAN; RNF 166; RNF166; Zfp313l; Zinc finger protein 228; Zinc finger protein 313;MGC14381;MGC2647;ring finger protein 166; 宿主 Rabbit 稀释比例 IHC 1:50-200. Gene ID 115992 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q96A37 蛋白分子量 14/17/26kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm 免疫原 Recombinant protein of human RNF166 亚型 IgG 纯化方法 Affinity purification 背景资料 E3 ubiquitin-protein ligase that promotes the ubiquitination of different substrates (PubMed:27880896).In turn, participates in different biological processes including interferon production or autophagy (PubMed:26456228, PubMed:27880896).Plays a role in the activation of RNA virus-induced interferon-beta production by promoting the ubiquitination of TRAF3 and TRAF6 (PubMed:26456228).Plays also a role in the early recruitment of autophagy adapters to bacteria (PubMed:27880896).Mediates 'Lys-29' and 'Lys-33'-linked ubiquitination of SQSTM1 leading to xenophagic targeting of bacteria and inhibition of their replication (PubMed:27880896). Public Immunogen Range 1-238aa 克隆类型 Polyclonal Antibody 交叉反应 Human;Mouse;Rat 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。