英文名称 Anti-MEOX1 Polyclonal Antibody 靶标 MEOX1 别名 MOX1 宿主 Rabbit 预测交叉反应 Zebrafish;Chimpanzee 稀释比例 WB 1:1000-3000;IHC 1:100-300. Gene ID 4222 Swiss Prot P50221 保存 Store at -20°C. Avoid freeze / thaw cycles. 蛋白分子量 16/20/28kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm Nucleus 免疫原 Recombinant protein of human MEOX1 亚型 IgG 纯化方法 Affinity purification 背景资料 Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints (PubMed:23290072, PubMed:24073994). Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome. Public Immunogen Range 1-255aa 克隆类型 Polyclonal Antibody 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。