靶标 STAM2 别名 DKFZp564C047;Hbp;Hrs-binding protein;HSE1 homolog;Signal transducing adapter molecule 2;Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2;Signal transducing adaptor molecule 2A;Signal transducing adaptor molecule 2B;Signal transducing adaptor molecule;STAM like protein containing SH3 and ITAM domains 2;STAM-2;Stam2;STAM2_HUMAN;STAM2A;STAM2B 宿主 Rabbit 稀释比例 WB 1:1000-3000.;IHC 1:50-200. Gene ID 10254 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot O75886 蛋白分子量 38/58kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. 亚细胞定位 Cytoplasm Nucleus 免疫原 A synthetic peptide of human STAM2 亚型 IgG 纯化方法 Affinity purification 背景资料 Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity). Public Immunogen Range 180-230/525aa 克隆类型 Polyclonal Antibody 交叉反应 Human 应用 WB;IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。