英文名称 Anti-MORF4L1 Polyclonal Antibody 靶标 MORF4L1 别名 MORF4L1;Eaf3;FWP006;HsT17725;MEAF3;MORFRG15;MRG15;S863-6;mortality factor 4 like 1 宿主 Rabbit 预测交叉反应 Gorilla 稀释比例 WB 1:1000-3000. Gene ID 10933 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q9UBU8 蛋白分子量 27/37/41kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Nucleus 免疫原 Recombinant protein of human MORF4L1 亚型 IgG 纯化方法 Affinity purification 背景资料 Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction； tumor suppressor mediated growth arrest and replicative senescence； apoptosis； and DNA repair. The NuA4 complex ATPase and helicase activities seem to be； at least in part； contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2； BRCA2 and RAD51； but not BRCA1； to DNA-damage foci. Public Immunogen Range 1-324aa 克隆类型 Polyclonal Antibody 交叉反应 Human;Mouse;Rat 应用 WB 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。