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Solarbio K111927P Anti-PRKAG1 Polyclonal Antibody

销售价:
¥768.00
市场价:
¥960.00
编号:
202302241034307
货号:
K111927P-50ul
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产品规格:
100ul 50ul
数量:

商品介绍

靶标 PRKAG1 别名 5' AMP activated protein kinase gamma 1 subunit;5' AMP activated protein kinase subunit gamma 1;5''-AMP-activated protein kinase subunit gamma-1;AAKG1_HUMAN;AMP activated protein kinase noncatalytic gamma 1 subunit;AMPK gamma 1 chain;AMPK gamma1;AMPK subunit gamma-1;AMPKg;MGC8666;PRKAG 1;PRKAG1;Protein kinase AMP activated gamma 1 non catalytic subunit;protein kinase, AMP-activated, noncatalytic gamma-1 宿主 Rabbit 预测交叉反应 Bovine;Pig 稀释比例 IHC 1:100-300. Gene ID 5571 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot P54619 蛋白分子量 34/38/39kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.4. 亚细胞定位 Cytoplasm Nucleus Cell membrane 免疫原 Recombinant protein of human PRKAG1 亚型 IgG 纯化方法 Affinity purification 背景资料 AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive. Public Immunogen Range 1-332aa 克隆类型 Polyclonal Antibody 交叉反应 Human;Mouse;Rat 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。

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品牌 Solarbio

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