来源于牛跟腱。可作为胶原酶的底物。Ⅰ型胶原蛋白是皮肤、骨骼、肌腱以及其他纤维连接组织的组成成分。Product DescriptionThis product is suitable for use as a substrate for collagenase. It is prepared by modification of the method of Einbinder and Schubert and is not suitable for use in coating glassware.This collagen is Bornstein and Traub Type I. The Type I classification of collagen is a component of skin, bone, tendon, and other fibrous connective tissues. Type I collagen differs from other collagens by their low lysine hydroxylationand low carbohydrate composition.Collagen breaks down metabolically in the body to release N-telopeptide, which is the N-terminus of collagen. There is also C-telopeptide, which is presumably the C-terminus. N-telopeptide is released in urine, and its detection in diagnostic tests is used to screen for osteoporosis.Although different types of collagen exist, they are all composed of molecules containing three polypeptide chains arranged in a triple helical conformation. Slight differences in the primary structure (amino acid sequence) establish differences between the types. The amino acid sequence of the primary structure is mainly a repeating motif with glycine in every third position and proline or 4-hydroxyproline frequently preceeding the glycine residue.Preparation InstructionsThis product is an insoluble collagen preparation. It is insoluble in water, aqueous buffers, dilute acid, and organic solvents. For use as a substrate in collagenase assays, this collagen can be prepared as a suspension in 50 mM TES buffer, pH 7.4 with 0.36 mM calcium chloride. but not a clear solution.Storage/StabilityIt is recommended to store this product at 2–8 °C. If stored as recommended, it will have a shelf-life of up to 8 years.Precautions and DisclaimerFor Laboratory Use Only. Not for drug, household or other uses.备注：产品信息可能会有优化升级。请以实际标签信息为准。备注：以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。These protocols are for reference only. Solarbio does not independently validate these tmethods.